Enhancer Steroids Excessive Dutasteride Hair Growth CAS 164656-23-9

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Enhancer Steroids Dutasteride CAS 164656-23-9 for Excessive Hair Growth



Product Name: Dutasteride
Synonyms: (5alpha,17beta)-n-{2,5-bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-l-ene-17-carboxamide;DUTASTERIDE;GG-745, GI-198745,;5,17)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4- Aza -androst-1-ene-17-carboxamide;Duagen;(5a,17)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-1-ene-17-carboxamide;Avodart;GI 198745
CAS: 164656-23-9
MF: C27H30F6N2O2
MW: 528.53



Dutasteride Medical uses



1. Prostate enlargement


Dutasteride is occasionally used for treating benign prostatic hyperplasia (BPH); colloquially known as an "enlarged prostate".It is approved by the Food and Drug Administration (FDA) in the U.S. for this indication.



2. Prostate cancer


In those who are being regularly screened, 5-reductase inhibitors such as finasteride and dutasteride reduce the overall risk of being diagnosed with prostate cancer; however, there is insufficient data to determine if they have an effect on the risk of death and may increase the chance of more serious cases.



3.Pattern hair loss


Dutasteride is approved for the treatment of male androgenetic alopecia in South Korea at a dosage of 0.5 mg per day.It has been found in several studies to improve hair growth in men more rapidly and to a greater extent than 2.5 mg/day finasteride.Dutasteride has also been used off-label in the treatment of female pattern hair loss.



4. Excessive hair growth


Although no reports specific to dutasteride currently exist,5-reductase inhibitors like finasteride have been found to be effective in the treatment of hirsutism (excessive facial and/or body hair growth) in women.In a study of 89 women with hyperandrogenism due to persistent adrenarche syndrome, finasteride produced a 93% reduction in facial hirsutism and a 73% reduction in bodily hirsutism after 2 years of treatment.Other studies using finasteride for hirsutism have also found it to be clearly effective.Dutasteride may be more effective than finasteride for this indication due to the fact that its inhibition of the 5-reductase enzyme is comparatively more complete.



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