Pharmaceutical Ingredient Sitagliptin Phosphate Intermediate Chemicals CAS 76224

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Manufacturer
Country
China
Category

Product Detail

Pharmaceutical Ingredient Sitagliptin Phosphate Intermediate Chemicals CAS 762240-92-6 Product Info : Molecular Formula: C6H7F3N4.HCl CAS Registry Number: 762240-92-6 Usage: An intermediate of sitagliptin phosphate About sitagliptin phosphate : As an orally active agent, Sitagliptin phosphate exhibits a potent inhibitory effect on DPP-4 with IC50 of 19 nM from Caco-2 cell extracts. MK0431 reduces in vitro migration of isolated splenic CD4 T-cells through a pathway involving cAMP/PKA/Rac1 activation. A recent study demonstrates that sitagliptin exerts a novel, direct action in order to stimulate GLP-1 secretion by the intestinal L cell through a DPP-4-independent, protein kinase A- and MEK-ERK1/2-dependent pathway. It therefore reduces the effect of autoimmunity on graft survival. Packaging: (1) 10g/100g/500g/1kg, packaged by Aluminum foil bag. (2) Customized package. Chemical Properties: - - - - Appearance | white or off white power | Molecular Weight | 228.60 | Molecular Structure | | Density | 1.468 g/cm3 | Boiling Point | 266.2 C at 760 mmHg | Melting Point | 236-246C | Flash Point | 114.8 C | Storage Temperature | Refrigerator | - - - - Safety Information: - - - - Hazard Codes | [Xi] | Risk Statements | [37/38-41] | Safety Statements | [26-39] | Hazard Note | Irritant | HazardClass | IRRITANT | - - - - FAQ: Q1: Are you a manufacturer? A: Yes, We manufacture bulk products in our factory located in Jiayu, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan. Q2: Do you have stock? A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize. Q3: What certificates and documents do you offer? A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc. Q4: Why should I choose you? A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5 years, in average. Strict quality control-comes form our sophisticated management system. Professional and warm sales team-since we believe we can only win via our hard work in a competitive world Quick response and excellent presale and after sale service-since we believe our customers deserve all the best service Q5: Can I get best price from you? A: Of course. We don't chase excessive profits and always try tp give best offer. If you are good at bargaining, you can also enjoy fun of bargaining. Just don't make it too hard! Q6: How should I pay? A: We accept all kinds of payment ways. such as alibaba trade asssurance, T/T, West union, Paypal. Q7: Do you provide free sample? A: Yes, we can provide free sample if we have in stock, just need you to cover the delivery cost.

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Manufacturer
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Products
Pharma Intermediates, Solvent

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Wuhan Vanz Pharm Inc.

Ms. du du

China

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